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The POCT devices currently under development (Applications)

Respiratory disease (pneumonia) screening device

 

Overview

For many infectious diseases, beginning of treatment is required at a stage when the pathogens (such as viruses, bacteria, fungi, parasites, etc.) that cause the disease are still unknown. Therefore, although the development of technology for identifying the causes of these infections quickly is much needed, a system that can comprehensively detect a wide range of pathogens has not yet been put into practice.

Among these infections, pneumonia is Japan's third largest cause of death (according to the "2013 vital statistics" of the Ministry of Health, Labor and Welfare) and thus an extremely serious infection. Administering the most efficient antibiotics against the pathogens is indispensable in the treatment of infectious diseases. However, when using the culture method that is the current standard testing method, it takes several days to determine whether the patient carries the pathogens or not, and it is practically impossible to quickly determine which antibiotic needs to be administered. In the case of rapidly progressing pneumonia, this situation can prove to be fatal.

On the other hand, if we could determine immediately the pathogen that is the cause and quickly select an appropriate antibiotic and administer it, the effectiveness of the treatment would be greatly improved. This is the reason why we are now applying our platform technology to develop a screening device that identifies multiple bacteria that cause pneumonia in a short period of time with a high-speed PCR.

 

Our solution

Existing analytical methods make it hard to quickly identify a wide range of pneumonia pathogenic microorganisms, so these methods have not been able to respond well to medical needs. However, by using the CAs-CHIP platform to achieve "short time" and "multi-type" testing at the same time, in the case of pneumonia testing, screening can be done within 15 minutes and we can meet the requirement for "rapid infection diagnosis".



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